PROSPeCT: Improving the prediction of metastatic disease in primary colorectal cancer via prognostic modelling of conventional and novel variables from perfusion CT

The PROSPeCT trial has completed recruitment. Many thanks to all those who made this possible. Patient follow-up is ongoing.

This prospective multicentre cohort study, funded by the National Institute for Health Research Health Technology Assessment programme was led by Professor Vicky Goh from King’s College London, and delivered by a group of BSGAR investigators.

Study objective:

PROSPeCT was designed with the following primary objective: To improve the prediction of metastatic disease in patients with colorectal cancer by developing a prognostic model based on disease free survival via prospective evaluation of both conventional predictive variables and novel variables derived from Perfusion CT.


Recruitment to PROSPecT has closed with 447 patients recruited, and follow-up is ongoing.


Questions about the PROSPeCT study should be directed to the Team at the following address:

PROSPeCT Study Co-ordinator

Cancer Clinical Trials Unit Scotland, Edinburgh

Email: [email protected]


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