PERFECTS (PERFormance and Evaluation for CT colonography Screening) is a multicentre, prospective cluster randomised trial that began in 2017.  The aim is to determine if delivery of a structured educational programme with individualized feedback can improve reader diagnostic performance.

PERFECTS has now closed to recruitment. Follow-up is ongoing. Many thanks to all who are participating in the study.

The study is co-led by Dr David Burling from St Mark’s Hospital and Dr Andrew Plumb from University College London. Funding is from the St Mark’s Hospital Foundation, supported by the charities 40tude, the Edith Murphy Foundation and the Peter Stebbings Memorial Charity

Primary objective:
To determine whether an individualised educational training programme improves diagnostic sensitivity for colorectal cancer and polyps for radiologists who are already performing CT colonography in their routine clinical practice.

Key secondary objectives:
•    To determine if the educational programme improves diagnostic specificity.
•    To determine the durability of these changes at 6 and 12 months follow-up.
•    To identify key radiologist factors associated with superior diagnostic performance.
•    To investigate the relationship between interpretation technique and diagnostic accuracy.

The study has closed to recruitment after randomising 130 radiologists. For further details, please contact:

c/o Dr Anu Obaro
Intestinal Imaging Centre
St Mark’s Hospital
email: [email protected] OR [email protected] OR [email protected]



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